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Higher melatonin in the follicle fluid and MT2 expression in the granulosa cells contribute to the OHSS occurrence.

Reprod Biol Endocrinol · 2019 · PMC6461819 · PMID 30979376

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A prospective clinical trial showed that although the differences did not reach statistical significance, the clinical pregnancy rate and implantation rate were in a high tendency in the group treated with melatonin [ 29 ].

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