Whole Egg Consumption Impairs Insulin Sensitivity in a Rat Model of Obesity and Type 2 Diabetes.

Insulin signaling pathway Insulin increased phosphorylation of the IR β Tyr1150/1151 by 291% in lean rats fed the whole egg–based diet compared with IR β Tyr1150/1151 phosphorylation prior to insulin ( Figure 2 ); however, post-insulin IR β Tyr1150/1151 phosphorylation did not reach statistical significance ( P = 0.215) in lean casein-fed rats compared with pre-insulin phosphorylated insulin receptor (p-IR) β Tyr1150/1151 .

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