Barely Significant
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Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.

Oncogene · 2019 · PMC6462854 · PMID 30353166

Europe PMCDOI
1
hedged sentence
0.0512
closest p · 1.0× alpha
0.0512
boldest claim

The sentences

approached significancep = 0.0512so close (0.05 < p ≤ 0.1)
The combination led to an improved median survival of 74.5 d, which approached significance ( p = 0.0512), versus 52.5 d with trametinib alone, 42 d with JQ1 alone (both not significant) when compared with 44.5 d with vehicle (Figure S9B ).

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