Though we demonstrate that this BMI-related increase in Gaussian curvature is mediated by white matter, the white matter signal intensity, as a proxy measure for white matter integrity obtainable from T1-weighted MRI, was not an equally reliable indicator of BMI-linked brain structure changes, given that in dataset C it only showed a trend-like association with BMI.
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BMI-related cortical morphometry changes are associated with altered white matter structure.
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