ABCA7 Risk Genotype Diminishes the Neuroprotective Value of Aerobic Fitness in Healthy Older African Americans.

Although the association of ABCA7 rs3764650 with AD has been confirmed in Caucasians (Harold et al., 2009 ; Lambert et al., 2010 ; Carrasquillo et al., 2011 ; Hollingworth et al., 2011 ; Omoumi et al., 2014 ; Cuyvers et al., 2015 ), GWAS studies in African Americans have found either none, or a nominally significant association (Logue et al., 2011 ; Reitz et al., 2013 ; N’songo et al., 2017 ).

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