Drug Transport across Porcine Intestine Using an Ussing Chamber System: Regional Differences and the Effect of P-Glycoprotein and CYP3A4 Activity on Drug Absorption.

Pharmaceutics · 2019 · PMC6471532 · PMID 30901927

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a clear trendno p-value reported

Highly lipophilic molecules, e.g., midazolam, tamoxifen and verapamil, used in the studies to investigate CYP3A4 activity showed a clear trend towards accumulation within the membrane.

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