Synthesis, In Vitro Antimicrobial and Cytotoxic Activities of Some New Pyrazolo[1,5-<i>a</i>]pyrimidine Derivatives.

Molecules · 2019 · PMC6471749 · PMID 30893820

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slightly significantno p-value reported

In addition, the compounds 3a , b , 5a , 7a , b , 9b , 11a , and 12a had slightly significant effects with IC 50 values ranging from 14.1 to 38.5 μg, the compound 3a indicated a slightly noticeable effect on HePG2 cells with IC 50 of 6.1 μg, and the compound 12a had weak toxicity on HCT 116 cells with IC 50 of 46.1 μg.

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