BRCA1 mutations attenuate super-enhancer function and chromatin looping in haploinsufficient human breast epithelial cells.

Breast Cancer Res · 2019 · PMC6472090 · PMID 30995943

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showed a trendno p-value reported

MED1 chromatin binding at the BRCA1 mutation-affected super-enhancers showed a trend of decrease, albeit statistically insignificant, in BRCA1 185delAG/+ MCF10A clones versus the WT control (Fig. 4 c).

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