Compared with gefitinib and erlotinib, afatinib treatment yielded a longer PFS for patients with uncommon EGFR mutations, although this difference did not reach statistical significance, possibly due to the small sample size (p=0.06).
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Efficacy and Safety of Afatinib for EGFR-mutant Non-small Cell Lung Cancer, Compared with Gefitinib or Erlotinib.
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0.0600