Barely Significant
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A Neuron-Glial Trans-Signaling Cascade Mediates LRRK2-Induced Neurodegeneration.

Cell Rep · 2019 · PMC6474846 · PMID 30759389

Europe PMCDOI
1
hedged sentence
0.0690
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0.0690
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a strong trendp = 0.069so close (0.05 < p ≤ 0.1)
In support of our genetic results, we found that overexpression of LRRK2 IT led to a significant enhancement of pMad accumulation in the nuclei of glia surrounding DA neurons but not in DA neurons themselves ( Figures 5L–5N ). Similarly, we found that pMad accumulation in glial cells showed a strong trend toward enhancement (15% increase in mean pMad fluorescence intensity; p = 0.069) as a result of exposure to paraquat.

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