Rationale, design and study protocol of the randomised controlled trial: Diabetes Interventional Assessment of Slimming or Training tO Lessen Inconspicuous Cardiovascular Dysfunction (the DIASTOLIC study).

BMJ Open · 2019 · PMC6475184 · PMID 30928925

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a strong trendno p-value reported

There were elevated inflammatory markers (high sensitivity C-reactive protein (hsCRP), interleukin-6 and 10 and tumour necrosis factor-alpha), reduced adiponectin and a strong trend for concentric remodelling (increased LV mass/volume) in both the T2D and obese controls versus the lean controls.

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