3 Few studies have addressed the trends in the prevalence of airflow limitation over time based on the data from repeated community-based surveys, although the nationwide surveys in the USA showed a decreasing trend in the prevalence of airflow limitation. 4 Tobacco smoke, indoor and outdoor air pollutants and occupational dust have been acknowledged as major risk factors for airflow limitation along with genetic factors such as alpha 1 -antitrypsin deficiency, 5 but there has been no survey assessing the associations of risk factors with the prevalence of airflow limitation in a time series manner.
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Trends in the prevalence of airflow limitation in a general Japanese population: two serial cross-sectional surveys from the Hisayama Study.
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The sentences
In the present study, the magnitude of the association between male sex and the airflow limitation in 2012 was significantly greater than that in 1967, although the OR for each survey did not reach statistical significance.