Herpes simplex virus type 1 epidemiology in Latin America and the Caribbean: Systematic review and meta-analytics.

PLoS One · 2019 · PMC6476500 · PMID 31009486

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did not reach statistical significanceno p-value reported

There was evidence here for a statistically-significant declining seroprevalence over time by 0.99-fold (95% CI: 0.99–0.99) per year, in contrast to the first model analysis ( Table 3 ) and the analyses including the year of publication as a category ( S3 Table ), where the evidence for the decline in sero-prevalence did not reach statistical significance.

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