Coadministration of A1M displayed significantly reduced messenger RNA (mRNA) expression, compared with the 177 Lu-DOTATATE animals, of Bax and a clear trend toward reduced expression of all other genes evaluated.
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Protection of Kidney Function with Human Antioxidation Protein α<sub>1</sub>-Microglobulin in a Mouse <sup>177</sup>Lu-DOTATATE Radiation Therapy Model.
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However, in a new experiment, urine albumin was corrected for with creatinine levels and had a decreasing trend with coadministration of A1M compared with animals receiving only 177 Lu-DOTATATE ( Supplementary Fig.