showed a trendp < 0.06
Patients with high-level IL-6 plus PTGER2 plus PTGER4 showed a trend to reduced distant metastasis-free survival (DMSF, p < 0.06 , Fig. 7 d), and a significant reduction in OS ( p = 0.0045 , Fig. 7 e), compared to patients with low-level IL-6 plus PTGER2 plus PTGER4.