Establishment and characterization of a radiation-induced dermatitis rat model.

Hair follicle density was significantly reduced at both 4 and 12 weeks post‐irradiation compared with that of the control (5.10 ± 1.62 hairs/mm 2 , n = 9 and 24.55 ± 3.43 hairs/mm 2 , n = 9, respectively; both P < 0.01, Figure 2 F).The sebaceous glands density was significantly reduced compared with that of the control at 4 weeks post‐irradiation (0.46 ± 0.13 hairs/mm 2 , n = 9, P < 0.01), and also showed a decreased tendency at 12 weeks but did not reach statistical significance (Figure 2 G).

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