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Oxaliplatin aggravates hepatic oxidative stress, inflammation and fibrosis in a non‑alcoholic fatty liver disease mouse model.

Int J Mol Med · 2019 · PMC6488186 · PMID 30942432

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There was also a modest increase in α-smooth muscle actin (SMA) and tissue inhibitor of metallopeptidase (TIMP)-1 expression 6 days after administration of the first dose of OXA, but these differences did not reach statistical significance ( Fig. 5D and E ).

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