Excess risk of preterm birth with periconceptional iron supplementation in a malaria endemic area: analysis of secondary data on birth outcomes in a double blind randomized controlled safety trial in Burkina Faso.

Malar J · 2019 · PMC6501288 · PMID 31060615

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did not reach statistical significanceno p-value reported

Approximately half of all placentae had histological evidence of past malaria infection, and chronic placental malaria was more frequent in women receiving iron although this difference did not reach statistical significance (adjusted RR = 1.30, P adj = 0.25, Table 2 ).

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of borderline significanceno p-value reported

Birth outcomes by trial arm The mean birthweight was 100 g lower in the iron group (95% CI 205:5), P adj = 0.033), with a greater risk of LBW (OR: 1.34 (0.99–1.81) of borderline significance (P = − 0.062) (Table 2 ).

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