Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly.

Although there was a trend toward an expansion in proportion of immature erythroid cells in the PTPRT/HCK mice it did not reach statistical significance, possibly due to the small sample size (Fig. 6B ).

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