Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production.

Oncotarget · 2019 · PMC6505628 · PMID 31105869

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did not reach statistical significanceno p-value reported

N-RAS-transformed iMEFs, in contrast, showed reduced proliferation in response to (R)-2-HG, but this effect did not reach statistical significance.

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