Moreover, the influence of SOX2 binding was evident by comparing group 1 genes connected to enhancers bound by SOX2, which yielded highly significant coassociation scores (lanes 2, 6, and 10), with those connected to enhancers not bound by SOX2 (lanes 3, 7, and 11), which yielded only marginally significant scores in wTR1 and nonsignificant scores in wTR2 and wTR3.
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Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance.
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