Alternative cleavage and polyadenylation of genes associated with protein turnover and mitochondrial function are deregulated in Parkinson's, Alzheimer's and ALS disease.

BMC Med Genomics · 2019 · PMC6507032 · PMID 31072331

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a significant trendno p-value reported

These results show that different genes exhibit significant APA in different regions of the AD brain, but all show a significant trend to 3’UTR lengthening.

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an overall trendno p-value reported

We found that around 700 genes (2.7%) of genes showed significant APA changes, and an overall trend to 3’UTR lengthening was observed in patient derived RNA.

also in 4,871 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.