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ALK2 inhibitors display beneficial effects in preclinical models of <i>ACVR1</i> mutant diffuse intrinsic pontine glioma.

Commun Biol · 2019 · PMC6509210 · PMID 31098401

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There was enrichment for PIK3CA mutations in R258G tumours, and PIK3R1 in G356D (log2 odds ratios >2.5), however this failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.