Novel CMKLR1 Inhibitors for Application in Demyelinating Disease.

Sci Rep · 2019 · PMC6509344 · PMID 31073181

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showed a trendno p-value reported

β-arrestin2 assay showed a trend in the activity of these compounds decreasing in the following order: α-naphthyl ( 22 , IC 50 2.3 μM) > β-naphthyl ( 23 , IC 50 3.1 μM) >phenyl ( 24 , IC 50 4.3 μM) >cyclohexyl ( 25 , IC 50 11.9 μM) (Table 3 ).

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