Combined Effect of Fatty Diet and Cognitive Decline on Brain Metabolism, Food Intake, Body Weight, and Counteraction by Intranasal Insulin Therapy in 3×Tg Mice.

Front Cell Neurosci · 2019 · PMC6509878 · PMID 31130848

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a significant trendno p-value reported

Cognitive Function In 8 months old mice ( Figure 5A ) a significant trend toward cognitive dysfunction was found across groups, from C-ND to C-HFD to 3×Tg-ND to 3×Tg-HFD.

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did not achieve significanceno p-value reported

The reduction in dentate gyrus and granule cell layer dimensions did not achieve significance in 8 months old HFD and 3×Tg mice, showing only a tendency.

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