It followed that their depletion by clodronate showed a strong trend toward reducing cord branching, indicating that the macrophage progeny of Sca-1 + CD45 + progenitors acted as vascular fusion cells to support endothelial tip cell anastomosis, as has been described by others 18 .
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Vasculogenic properties of adventitial Sca-1<sup>+</sup>CD45<sup>+</sup> progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis.
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