Non-invasive Motor Cortex Neuromodulation Reduces Secondary Hyperalgesia and Enhances Activation of the Descending Pain Modulatory Network.

Front Neurosci · 2019 · PMC6519323 · PMID 31139047

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0800

boldest claim

The sentences

highly significantp < 0.0001actually significant

Due to the increase in pain intensity ratings during exposure to the C-HP model the time factor was highly significant ( t -stat = 9.5; p < 0.0001).

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did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Furthermore, these subjects experienced a greater reduction in mean area of secondary hyperalgesia after anodal tDCS (19 cm 2 ) compared to cathodal (9 cm 2 ) or sham (4 cm 2 ) stimulation, although this difference did not reach statistical significance (anodal versus sham t -stat = -1.8, p = 0.08; anodal versus cathodal t -stat = -1.5, p = 0.15).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.