The combined treatment LPS-Dex significantly down-regulated the LPS-induced IL1B and IL6 expression in 7-day (p = 0.04 and p = 0.004, respectively) and IL6 expression in 14-day culture macrophages (p = 0.04) (Figs 3 – 5 lower panel), while the expression of IL1A , at all-time points, IL1B in 14- and 21-day and IL6 in 21-day culture macrophages was reduced, although did not reach statistical significance.
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Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages.
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