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Vitamin D receptor rs7975232, rs731236 and rs1544410 single nucleotide polymorphisms, and 25-hydroxyvitamin D levels in Egyptian children with type 1 diabetes mellitus: effect of vitamin D co-therapy.

Diabetes Metab Syndr Obes · 2019 · PMC6526182 · PMID 31190930

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77 , 78 Notably, various studies have emerged recently to investigate possible association between VDR polymorphisms and T1DM, with conflicting results; some revealed significant associations, while, others failed to reach statistical significance. 79 The results of the current study revealed statistically significant association between Apa I and Bsm I polymorphisms allele and genotypic distributions and an increased risk of T1DM with nonsignificant association found regarding Taq I polymorphism.

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