Dissociating frontal and temporal correlates of phonological and semantic fluency in a large sample of left hemisphere stroke patients.

In addition, we further computed the above formulated contrasts for the within-patient comparison of the two fluency types separately for the left frontal and the left temporal patients: Patients with a left temporal lesion (red) showed a trend for producing fewer words in the semantic as compared to the phonological fluency condition (M R ± SEM R , 71.89 ± 12.70 vs. 83.89 ± 15.44, p = .054), whereas patients with a left frontal lesion (blue) produced significantly fewer words in the phonological as compared to the semantic fluency condition (M R ± SEM R , 54.46 ± 10.47 vs. 84.69 ± 8.09, p < .001).

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phonological), and the total number of words produced as dependent variable revealed a significant two-way interaction of cue type × lesion location (F 1.85,∞ = 6.310, p = .003) whereas the main effects of lesion location (F 1.66,∞ = 1.875, p = .161) and cue type (F 1.00,∞ = 2.459, p = .117) failed to reach significance.

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