A similar trend was observed in HT1080 cells although differences did not reach statistical significance (Fig. 5 c).
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<i>Isocitrate dehydrogenase 1</i>-mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallate.
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Higher irradiation doses resulted in increased levels of γH2AX, and there was a slight trend towards increased γH2AX levels after EGCG treatment of HCT116- IDH wt/R132H , but not HCT116, cells.