2018 Korean Liver Cancer Association-National Cancer Center Korea Practice Guidelines for the Management of Hepatocellular Carcinoma.

However, after adjusting for liver functional status, thrombocytopenia, varix, etc., the differences in the survival outcomes among the groups did not reach statistical significance. 324 Given the potential selection bias of the above-mentioned studies, TACE can be considered as an alternative treatment with curative intent when a patient refuses surgical treatment, or is at high risk for undergoing surgery, or HCC is not suitable for RFA.

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