The PRINTO evidence-based proposal for glucocorticoids tapering/discontinuation in new onset juvenile dermatomyositis patients.

Pediatr Rheumatol Online J · 2019 · PMC6530070 · PMID 31118099

Europe PMC DOI

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a clear trendno p-value reported

After treatment initiation, the three groups significantly differentiated over time, with a clear trend given by a sharp decrease in disease activity parameters, which was particularly evident when the reference Group 1 was compared with the other two groups.

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very close to statistical significanceno p-value reported

A statistically significant trend over time can be recognized from month 4 especially between Group 1 (CR yes-TF no-PDN off) and Group 3 (CR no-TF yes-PDN on or off), in particular for MD global, parent global, DAS, CMAS, MMT (all p values < 0.001) and CHAQ (p value = 0.002), with the exception of PhS that is very close to statistical significance and starts to be significant from month 12 onward.

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