Genetic Variants Flanking the <i>FGF21</i> Gene Were Associated with Renal Function in Chinese Patients with Type 2 Diabetes.

However, a significant association with estimated glomerular filtration rate (eGFR) was detected: in the non-DKD group, rs838136 was significantly associated with eGFR under an additive model ( β = 0.013 ± 0.006, P = 0.0295, β was calculated for log 10 eGFR) as well as a recessive model ( P = 0.0385) and rs499765 was associated with eGFR under a dominant model ( P = 0.0411) and in the DKD group, rs499765 showed a trend toward association with eGFR under an additive model ( β = −0.022 ± 0.012, P = 0.0820, β was calculated for log 10 eGFR) and showed a significant association with eGFR under a dominant model ( P = 0.0182).

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