Barely Significant
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Voluntary wheel running activates Akt/AMPK/eNOS signaling cascades without improving profound endothelial dysfunction in mice deficient in α-galactosidase A.

PLoS One · 2019 · PMC6533039 · PMID 31120949

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Although the aortic endothelial relaxation to acetylcholine was slightly increased in EX, it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.