Also, coefficients such as: bone metastases, time between nephrectomy and treatment start or the size of extranodal metastases greater than 8.0 cm failed to reach statistical significance (p > 0.05) for OS impact.
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Metastatic Tumor Burden and Loci as Predictors of First Line Sunitinib Treatment Efficacy in Patients with Renal Cell Carcinoma.
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