Physiological and morphological differences of airways between COPD and asthma-COPD overlap.

In addition, when adjusted for %LAA using logistic regression analyses (Supplementary Table S9 ), patients with ACO and COPD had differences in respiratory impedance and 3D-CT, similarly as observed in the original analysis (except that only ΔR5, ΔFres, and %WT in third-generation bronchi did not reach statistical significance), which suggested that physiological and morphological differences between ACO and COPD may be independent from emphysema.

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