Also, food restricted rats showed a trend toward an increase of NUCB2/nesfatin-1 (most antibodies do not distinguish between full length NUCB2 and nesfatin-1) protein expression in the PVN, ARC, LC, and DMH, while in rats with access to the running wheel only no altered expression of nesfatin-1 was observed compared to ad libitum fed control rats ( 75 ).
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Activity Based Anorexia as an Animal Model for Anorexia Nervosa-A Systematic Review.
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