Barely Significant
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Age-adjusted Charlson Comorbidity Index (ACCI) is a significant factor for predicting survival after radical gastrectomy in patients with gastric cancer.

BMC Surg · 2019 · PMC6537159 · PMID 31133008

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a decreasing trendno p-value reported
Background Although the incidence and mortality of GC showed a decreasing trend globally, [ 1 ], GC remains the fifth most common malignant tumor worldwide and the third leading cause of death (723,000 people die from GC, accounting for 8.8% of the world’s population) [ 2 ].

also in 47,180 other papers

showed a trendno p-value reported
However, high ACCI group still showed a trend of higher recurrence rate.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.