Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma.

Acad Pathol · 2019 · PMC6537274 · PMID 31206012

Europe PMC DOI

hedged sentence

0.0820

closest p · 1.6× alpha

0.0820

boldest claim

The sentences

did not reach statistical significanceP = .082so close (0.05 < p ≤ 0.1)

However, this result did not reach statistical significance ( P = .082), in contrast to the 2008 TCGA data. 22 O 6 -Methylguanine-DNA-methyltransferase promoter methylation must be assayed in each case, given the lack of absolute correlation with mutational profile or other tumor characteristics and its importance in predicting response to therapy.

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