5E ), showed a trend toward increased time spent exploring the open arms of an elevated plus maze ( Fig. 5F ), and diminished anxiety behavior as indicated by both reduced risk assessment and increased time spent in the bright arena of a Dark/Light maze ( Fig. 5G ).
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Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress.
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Exposure to a single stressor (Trauma alone) did not lead to the suppression of the CP and even led to a slight trend toward an elevation of gene expression of trafficking-related molecules ( Fig. 1B , ccl2 ).