OS cell sensitivity to CXCR4 antagonists CXCR4 mRNA expression (2 −ΔΔCT ) was significantly higher in U2OS (4.05, p = =0.04) and 143B (1052.7, p = =0.01) than in osteoblasts (0.03), while in SAOS-2 the difference of expression did not reach statistical significance (0.57, p == 0.6).
← all excerpts
CXCR4 in human osteosarcoma malignant progression. The response of osteosarcoma cell lines to the fully human CXCR4 antibody MDX1338.
1
0.6000
0.6000