Further analysis of patients in subgroups based on the number of antihypertensive drugs revealed a significant trend for increased LVH prevalence and higher PWV values with increased number of antihypertensive drugs (8.7 ± 2.9 m/s in the untreated group vs. 8.9 ± 2.0 m/s in patients treated with 1 drug vs. 9.5 ± 3.0 m/s in patients treated with 2 drugs vs. 9.4 ± 2.0 m/s in those treated with 3 drugs vs. 11.1 ± 3.5 m/s in patients treated with 4 drugs, p = 0.02).
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Arterial Stiffness in Patients With Renal Transplantation; Associations With Co-morbid Conditions, Evolution, and Prognostic Importance for Cardiovascular and Renal Outcomes.
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The study revealed a borderline significant association of donor aortic PWV with the composite outcome (occurrence of a fatal or nonfatal cardiovascular event and/or doubling of serum creatinine or development of ESRD) (RR 1.8, 95% CI 1 to 3.4, p = 0.05) in renal transplant recipients.