Diabetes downregulates renal adenosine A2A receptors in an experimental model of hypertension.

PLoS One · 2019 · PMC6544351 · PMID 31150459

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did not reach statistical significanceno p-value reported

Although this effect (50% increase) did not reach statistical significance, it is in the opposite direction as that reported in normotensive Sprague-Dawley rats, where STZ-induced diabetes decreased adenosine A 1 receptor immunostaining[ 21 ].

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