Dysregulation of a specific immune-related network of genes biologically defines a subset of schizophrenia.

5/37 marker-negative, non-clozapine-treated schizophrenia patients), albeit due to the small number of cases only at the level of a statistical trend at borderline significance ( p = 0.053), suggesting that, potentially, the marker combination could relate to a biological subset less susceptible to typical neuroleptic pharmacotherapy (Table 4 ).

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S3 for blood; S4 for splenocytes), although there was a strong trend toward increased T-cell number in tgDISC1 rats and significantly increased Cd3g expression, a pan T-cell marker, in PBMCs of the tgDISC1 rat (Supplementary Fig.

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