Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l.

Sci Rep · 2019 · PMC6547667 · PMID 31164666

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showed a trendno p-value reported

long-term (LT; lin − Sca-1 + cKit + CD48 − CD150 + ) repopulating HSCs as well as MPP1 (lin − Sca-1 + cKit + CD48 + CD150 + ) and MPP2 (lin − Sca-1 + cKit + CD48 + CD150 − ) cells, while the short-term (ST; lin − Sca-1 + cKit + CD48 − CD150 − ) repopulating HSCs showed a trend towards increased cell numbers (Fig. 3a,d ) 56 , 57 .

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