Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval in rats.

Elife · 2019 · PMC6548499 · PMID 31107241

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0930

boldest claim

The sentences

did not reach statistical significancep=0.057so close (0.05 < p ≤ 0.1)

CNO seemed to generally reduce the likelihood that lever pressing would be followed by food-cup approach, though this effect did not reach statistical significance (Drug effect, p=0.057).

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failed to reach significancep=0.093so close (0.05 < p ≤ 0.1)

If anything, intra-NAc injections of CNO tended to enhance the effect of the CS+ on this approach response, though this effect also failed to reach significance (Drug * Site * CS+ Period, p=0.093).

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