Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver.

Diol:epoxide ratios, which are a reflection of sEH activity, were also not significantly different between DMSO and control, although the ratio for the DHA metabolites (DiHDPE:EpDPE) was trending toward significance ( Figure 4B ).

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In addition, levels of two diols – 14,15-DiHETrE and 13,14-DiHDPE – were also lower in the DMSO group, although the decrease did not reach statistical significance ( Supplementary Table 1 ).

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