Tellurium Compounds Prevent and Reverse Type-1 Diabetes in NOD Mice by Modulating α4β7 Integrin Activity, IL-1β, and T Regulatory Cells.

Moreover, sub or supra-optimal concentrations of AS101 marginally delayed the onset of the disease, though these effects did not reach statistical significance This effect was accompanied by increased body weight ( Figure 5B ), and increased survival ( Figure 5C ) in mice receiving the optimal dose of 0.5 mg/kg.

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