Likewise, a decreasing trend in IL-12p40 secretion was observed after KLH and FLH treatment in Dectin-2 KO BMDCs compared with the secretion from WT BMDCs.
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TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals.
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Surprisingly, LPS treatment showed a trend toward a decreased proinflammatory cytokine secretion with both inhibitors, with a significant decline in IL-6 levels in cells treated with BAY 61-3606 ( Figure 4D ).